The galactic anticenter is opposite the Milky Way's center from our viewpoint on Earth. The closest bright star to the anticenter is Taurus the Bull's Elnath.
Blue-white Rigel shines as the brightest star in the constellation Orion the Hunter. It's a hot massive star, that someday will explode as a supernova.
The 6th-brightest star in the night sky, Capella, in the Northern Hemisphere constellation Auriga the Charioteer, is also a point of the Winter Hexagon.